Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence diversity of the leukotoxin (lktA) gene in caprine and ovine strains of Mannheimia haemolytica.

The Veterinary record - 20 Apr 2013

Vougidou C, Sandalakis V, Psaroulaki A, Petridou E, Ekateriniadou L

Abstract excerpt

Mannheimia haemolytica is the aetiological agent of pneumonic pasteurellosis in small ruminants. The primary virulence factor of the bacterium is a leukotoxin (LktA), which induces apoptosis in susceptible cells via mitochondrial targeting. It has been previously shown that certain lktA alleles are associated either with cattle or sheep. The objective of the present study was to investigate lktA sequence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Gene Amplification
Share to Goat Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemolysin Proteins

Share to Sheep Diseases

Share to Virulence Factors

Source

Identifiers

PMID: 23396525
DOI: 10.1136/vr.101014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence diversity of the leukotoxin (lktA) gene in caprine and ovine strains of Mannheimia haemolytica.PMID 23396525Read ↗

Sequence diversity and molecular evolution of the leukotoxin (lktA) gene in bovine and ovine strains of Mannheimia (Pasteurella) haemolytica.Semantic proximity Read ↗

Cytotoxic activity of Mannheimia haemolytica strains in relation to diversity of the leukotoxin structural gene lktA.Semantic proximity Read ↗

Mosaic structure and molecular evolution of the leukotoxin operon (lktCABD) in Mannheimia (Pasteurella) haemolytica, Mannheimia glucosida, and Pasteurella trehalosi.Semantic proximity Read ↗

Sequence diversity, cytotoxicity and antigenic similarities of the leukotoxin of isolates of Mannheimia species from mastitis in domestic sheep.Semantic proximity Read ↗

Ovine Mannheimia haemolytica isolates from lungs with and without pneumonic lesions belong to similar genotypes.Semantic proximity Read ↗

Phylogenetic diversity of Pasteurellaceae and horizontal gene transfer of leukotoxin in wild and domestic sheep.Semantic proximity Read ↗

Antimicrobial Susceptibility and Resistance Mechanisms in Mannheimia haemolytica Isolates From Sheep at SlaughterSemantic proximity Read ↗

A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxinSemantic proximity Read ↗

Molecular Characterization of Equine Isolates of Streptococcus pneumoniae : Natural Disruption of Genes Encoding the Virulence Factors Pneumolysin and AutolysinSemantic proximity Read ↗

Sequence diversity and molecular evolution of the heat-modifiable outer membrane protein gene (ompA) of Mannheimia(Pasteurella) haemolytica, Mannheimia glucosida, and Pasteurella trehalosi.Semantic proximity Read ↗

Evidence for vertical inheritance and loss of the leukotoxin operon in genus Mannheimia.Semantic proximity Read ↗

Multilocus sequence typing of a global collection of Pasteurella multocida isolates from cattle and other host species demonstrates niche association.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.