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Stx1 prophage excision in Escherichia coli strain PA20 confers strong curli and biofilm formation by restoring native mlrA.

FEMS microbiology letters - 1 Jul 2016

Uhlich Gaylen A, Chen Chin-Yi, Cottrell Bryan J, Hofmann Christopher S, Yan Xianghe, Nguyen Ly

Abstract excerpt

Prophage insertions in Escherichia coli O157:H7 mlrA contribute to the low expression of curli fimbriae and biofilm observed in many clinical isolates. Varying levels of CsgD-dependent curli/biofilm expression are restored to strains bearing prophage insertions in mlrA by mutation of regulatory genes affecting csgD Our previous study identified strong biofilm- and curli-producing variants in O157:H7 cultures that...

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PMID: 27190164
DOI: 10.1093/femsle/fnw123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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