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Article

Maternal PRKAA1 and EDNRA genotypes are associated with birth weight, and PRKAA1 with uterine artery diameter and metabolic homeostasis at high altitude.

Physiological genomics - 15 Sept 2014

Bigham Abigail W, Julian Colleen G, Wilson Megan J, Vargas Enrique, Browne Vaughn A, Shriver Mark D, Moore Lorna G

Abstract excerpt

Low birth weight and intrauterine growth restriction (IUGR) increase the risk of mortality and morbidity during the perinatal period as well as in adulthood. Environmental and genetic factors contribute to IUGR, but the influence of maternal genetic variation on birth weight is largely unknown. We implemented a gene-by-environment study wherein we utilized the growth restrictive effects of high altitude....

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Source

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Identifiers

PMID: 25225183
DOI: 10.1152/physiolgenomics.00063.2014
PMCID: PMC4166715

Genes

PRKAA1
EDNRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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