Evidence that parent‐of‐origin affects birth‐weight reductions at high altitude

Abstract excerpt

Hypoxia exerts a profound depressant effect on fetal growth, lowering birth weight, and raising mortality risk. Multigenerational high-altitude populations are relatively protected from this birth-weight decline, leading us to hypothesize that genetic factors were involved. We asked if the amount of high- versus low-altitude ancestry influenced birth weight at high altitude and, specifically, whether such...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Birth, Development, and Health
• Share to Epigenetics and DNA Methylation
• Share to Pregnancy and preeclampsia studies