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Article

Do anti-angiogenic or angiogenic factors contribute to the protection of birth weight at high altitude afforded by Andean ancestry?

Reproductive sciences (Thousand Oaks, Calif.) - 1 Sept 2010

Dávila R Daniela, Julian Colleen G, Wilson Megan J, Browne Vaughn A, Rodriguez Carmelo, Bigham Abigail W, Shriver Mark D, Vargas Enrique, Moore Lorna G

Abstract excerpt

OBJECTIVE: This prospective study was designed to determine whether variation in angiogenic (placental growth factor [PlGF]) and/or anti-angiogenic (soluble fms-like tyrosine kinase [sFlt-1]) factors contribute to the protective effect of highland ancestry (Andean) from altitude-associated reductions in fetal growth. STUDY DESIGN: Plasma sFlt-1 and PlGF levels, uterine artery (UA) blood flow, and fetal biometry...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20601535
DOI: 10.1177/1933719110372418
PMCID: PMC3035058

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