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Article

Mutations in Niemann Pick type C gene are risk factor for Alzheimer's disease.

Medical hypotheses - 1 Nov 2014

Kresojević Nikola, Dobričić Valerija, Svetel Marina, Kostić Vladimir

Abstract excerpt

Alzheimer's disease (AD) is the most common form of dementia characterized by deterioration of memory and other cognitive domains which leads to death in 3-9years after diagnosis. In addition to mutations in APP, PSEN1 and PSEN2 genes, that cause early onset autosomal dominant AD, several genetic risk factors for late onset AD are now known. There is another distinctive neurodegenerative lysosomal storage...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25220527
DOI: 10.1016/j.mehy.2014.08.025

Genes

NPC1
APP
NPC2
PSEN1
PSEN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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