Fordyce granules and hyperplastic mucosal sebaceous glands as distinctive stigmata in Muir-Torre syndrome patients: characterization with reflectance confocal microscopy.

doi:10.1111/jop.12256

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Article

Fordyce granules and hyperplastic mucosal sebaceous glands as distinctive stigmata in Muir-Torre syndrome patients: characterization with reflectance confocal microscopy.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Aug 2015

Ponti Giovanni, Meschieri Andrea, Pollio Annamaria, Ruini Cristel, Manfredini Marco, Longo Caterina, Mandel Victor D, Ciardo Silvana, Tomasi Aldo, Giannetti Luca, Pellacani Giovanni

Abstract excerpt

BACKGROUND: The Muir-Torre syndrome (MTS), a variant of Lynch syndrome (LS), is characterized by the presence of sebaceous skin adenomas and/or carcinomas and keratoacanthomas associated with visceral malignancies. Fordyce granules (FGs) are oral mucosal lesions previously found in association with LS. The aim of this study was to analyze the specific frequency of FGs in sporadic individuals and gene carriers...

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PMID: 25213213
DOI: 10.1111/jop.12256

Genes

MLH1
MSH2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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