Article
Carbapenem-resistant Enterobacteriaceae: biology, epidemiology, and management.
Annals of the New York Academy of Sciences - 1 Sept 2014
Temkin Elizabeth, Adler Amos, Lerner Anat, Carmeli Yehuda
Abstract excerpt
Introduced in the 1980s, carbapenem antibiotics have served as the last line of defense against multidrug-resistant Gram-negative organisms. Over the last decade, carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a significant public health threat. This review summarizes the molecular genetics, natural history, and epidemiology of CRE and discusses approaches to prevention and treatment.
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