Hox genes require homothorax and extradenticle for body wall identity specification but not for appendage identity specification during metamorphosis of Tribolium castaneum.

Abstract excerpt

The establishment of segment identity is a key developmental process that allows for divergence along the anteroposterior body axis in arthropods. In Drosophila, the identity of a segment is determined by the complement of Hox genes it expresses. In many contexts, Hox transcription factors require the protein products of extradenticle (exd) and homothorax (hth) as cofactors to perform their identity specification...

Topics

• Animal Structures
• Animals
• Body Patterning
• Gene Expression Regulation, Developmental
• Genes, Homeobox
• Homeodomain Proteins
• Insect Proteins
• Larva
• Metamorphosis, Biological
• Microscopy, Electron, Scanning