Article
Genetic variants of the vitamin K dependent coagulation system and intraventricular hemorrhage in preterm infants.
BMC pediatrics - 1 Sept 2014
Schreiner Christine, Suter Sévérine, Watzka Matthias, Hertfelder Hans-Jörg, Schreiner Felix, Oldenburg Johannes, Bartmann Peter, Heep Axel
Abstract excerpt
BACKGROUND: Pathogenesis of intraventricular hemorrhage (IVH) in premature infants is multifactorial. Little is known about the impact of genetic variants in the vitamin K-dependent coagulation system on the development of IVH. METHODS: Polymorphisms in the genes encoding vitamin K epoxide reductase complex 1 (VKORC1 -1639G>A) and coagulation factor 7 (F7 -323Ins10) were examined prospectively in 90 preterm...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
