Article
Candidate gene analysis: severe intraventricular hemorrhage in inborn preterm neonates.
The Journal of pediatrics - 1 Nov 2013
Adén Ulrika, Lin Aiping, Carlo Waldemar, Leviton Alan, Murray Jeffrey C, Hallman Mikko, Lifton Richard P, Zhang Heping, Ment Laura R
Abstract excerpt
Intraventricular hemorrhage (IVH) is a disorder of complex etiology. We analyzed genotypes for 7 genes from 224 inborn preterm neonates treated with antenatal steroids and grade 3-4 IVH and 389 matched controls. Only methylenetetrahydrofolate reductase was more prevalent in cases of IVH, emphasizing the need for more comprehensive genetic strategies.
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