Article
Genomic and transcriptomic analysis of NDM-1 Klebsiella pneumoniae in spaceflight reveal mechanisms underlying environmental adaptability.
Scientific reports - 28 Aug 2014
Li Jia, Liu Fei, Wang Qi, Ge Pupu, Woo Patrick C Y, Yan Jinghua, Zhao Yanlin, Gao George F, Liu Cui Hua, Liu Changting
Abstract excerpt
The emergence and rapid spread of New Delhi Metallo-beta-lactamase-1 (NDM-1)-producing Klebsiella pneumoniae strains has caused a great concern worldwide. To better understand the mechanisms underlying environmental adaptation of those highly drug-resistant K. pneumoniae strains, we took advantage of the China's Shenzhou 10 spacecraft mission to conduct comparative genomic and transcriptomic analysis of a NDM-1...
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