Cultivation-based multiplex phenotyping of human gut microbiota allows targeted recovery of previously uncultured bacteria.

Abstract excerpt

The human gut microbiota is linked to a variety of human health issues and implicated in antibiotic resistance gene dissemination. Most of these associations rely on culture-independent methods, since it is commonly believed that gut microbiota cannot be easily or sufficiently cultured. Here, we show that carefully designed conditions enable cultivation of a representative proportion of human gut bacteria,...

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