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Article

Common variants modify the age of onset for basal cell carcinomas in Gorlin syndrome.

European journal of human genetics : EJHG - 1 May 2015

Yasar Binnaz, Byers Helen J, Smith Miriam J, Lear John, Oudit Deemesh, Bholah Zaynab, Roberts Stephen A, Newman William G, Evans D Gareth

Abstract excerpt

Gorlin syndrome is an autosomal dominant disorder, characterized by multiple early-onset basal cell carcinomas (BCCs) and jaw keratocysts. Through association studies in cohorts of sporadic BCC, nine genetic variants have previously been identified to increase the risk of BCC. The nine SNPs were genotyped by Taqman allelic discrimination in 125 individuals with Gorlin syndrome. Kaplan-Meier survival curves and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25159867
DOI: 10.1038/ejhg.2014.167
PMCID: PMC4402640

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TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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