Article
Evaluation of the NucliSens EasyQ v2.0 assay in comparison with the Roche Amplicor v1.5 and the Roche CAP/CTM HIV-1 Test v2.0 in quantification of C-clade HIV-1 in plasma.
PloS one - 1 Jan 2014
Muenchhoff Maximilian, Madurai Savathee, Hempenstall Allison Jo, Adland Emily, Carlqvist Anna, Moonsamy Angeline, Jaggernath Manjeetha, Mlotshwa Busisiwe, Siboto Emma, Ndung'u Thumbi, Goulder Philip Jeremy Renshaw
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) genetic diversity poses a challenge to reliable viral load monitoring. Discrepancies between different testing platforms have been observed, especially for non-clade-B virus. Therefore we compare, in antiretroviral therapy (ART)-naïve South African subjects predominantly infected with HIV-1 clade-C, three commercially available assays: the COBAS AmpliPrep/COBAS TaqMan...
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