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Article

Bleeding and non-bleeding phenotypes in patients with GGCX gene mutations.

Thrombosis research - 1 Oct 2014

Watzka Matthias, Geisen Christof, Scheer Monika, Wieland Regina, Wiegering Verena, Dörner Thomas, Laws Hans-Jürgen, Gümrük Fatma, Hanalioglu Sahin, Unal Sule, Albayrak Davut, Oldenburg Johannes

Abstract excerpt

Functional limitations for the vitamin K cycle, caused either by mutations in gamma-glutamyl carboxylase or vitamin K epoxide reductase genes, result in hereditary deficiency of vitamin K-dependent coagulation factors (VKCFD1 and VKCFD2, respectively). Patients suffering from VKCFD often share several other anatomical irregularities which are not related to haemostasis. Here we report on nine patients, eight of...

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Source

Identifiers

PMID: 25151188
DOI: 10.1016/j.thromres.2014.07.004

Genes

GGCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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