Article
Large-scale genomic analysis of codon usage in dengue virus and evaluation of its phylogenetic dependence.
BioMed research international - 1 Jan 2014
Lara-Ramírez Edgar E, Salazar Ma Isabel, López-López María de Jesús, Salas-Benito Juan Santiago, Sánchez-Varela Alejandro, Guo Xianwu
Abstract excerpt
The increasing number of dengue virus (DENV) genome sequences available allows identifying the contributing factors to DENV evolution. In the present study, the codon usage in serotypes 1-4 (DENV1-4) has been explored for 3047 sequenced genomes using different statistics methods. The correlation analysis of total GC content (GC) with GC content at the three nucleotide positions of codons (GC1, GC2, and GC3) as...
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