Article
Prefronto-subcortical imbalance characterizes poor decision-making: neurochemical and neural functional evidences in rats.
Brain structure & function - 1 Nov 2015
Fitoussi Aurélie, Le Moine Catherine, De Deurwaerdère Philippe, Laqui Matéo, Rivalan Marion, Cador Martine, Dellu-Hagedorn Françoise
Abstract excerpt
A major challenge of decision-making research in recent years has been to develop models of poor decision-making to identify its neural bases. Toward this goal, we developed a Rat Gambling Task that discerns good and poor decision-makers in a complex and conflicting situation such as the human Iowa Gambling Task. Nothing is known about the role of the monoaminergic modulatory systems in shaping these phenotypes....
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