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Article

The interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases

18 Aug 2014

Abstract excerpt

The family of interferon regulatory factors (IRFs) consists of nine members (IRF1–IRF9) in mammals. They act as transcription factors for the interferons and thus exert essential regulatory functions in the immune system and in oncogenesis. Recent clinical and experimental studies have identified critically important roles of the IRFs in cardiovascular diseases, arising from their participation in divergent and...

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PMID: 25131895
DOI: 10.1111/bph.12881

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