Article
Trophectoderm DNA fingerprinting by quantitative real-time PCR successfully distinguishes sibling human embryos.
Journal of assisted reproduction and genetics - 1 Nov 2014
Scott Richard T, Su Jing, Tao Xin, Forman Eric J, Hong Kathleen H, Taylor Deanne, Treff Nathan R
Abstract excerpt
PURPOSE: To validate a novel and more practical system for trophectoderm DNA fingerprinting which reliably distinguishes sibling embryos from each other. METHODS: In this prospective and blinded study two-cell and 5-cell samples from commercially available sibling cell lines and excess DNA from trophectoderm biopsies of sibling human blastocysts were evaluated for accurate assignment of relationship using...
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