Article
Mutations in the 3c and 7b genes of feline coronavirus in spontaneously affected FIP cats.
Research in veterinary science - 1 Oct 2014
Borschensky C M, Reinacher M
Abstract excerpt
Feline infectious peritonitis (FIP) is the most frequent lethal infectious disease in cats. However, understanding of FIP pathogenesis is still incomplete. Mutations in the ORF 3c/ORF 7b genes are proposed to play a role in the occurrence of the fatal FIPV biotype. Here, we investigated 282 tissue specimens from 28 cats that succumbed to FIP. Within one cat, viral sequences from different organs were similar or...
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