Article
Field strain feline coronaviruses with small deletions in ORF7b associated with both enteric infection and feline infectious peritonitis.
Journal of feline medicine and surgery - 1 Jun 2009
Lin Chao-Nan, Su Bi-Ling, Huang Hui-Pi, Lee Jih-Jong, Hsieh Min-Wei, Chueh Ling-Ling
Abstract excerpt
Feline coronavirus (FCoV) varies greatly from causing subclinical or mild enteric infections to fatal feline infectious peritonitis (FIP). The open reading frame (ORF) 7b of FCoV has been speculated to play a determining role in virulence as deletions were found to be associated with avirulent viruses. To further clarify the correlation between this gene and FIP, clinical samples from 20 cats that had succumbed...
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