[Confirmation of 17 rare HLA alleles and prediction of their haplotypes].

doi:10.3760/cma.j.issn.1003-9406.2014.04.025

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Article

[Confirmation of 17 rare HLA alleles and prediction of their haplotypes].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2014

Zhu Chuanfu, Zhang Yi, Nie Xiangmin, Qiao Wenben, Song Yonghong, Liu Yan, Zhuang Yunlong

Abstract excerpt

OBJECTIVE: To confirm 17 rare HLA alleles detected during routine HLA typing and deduce their haplotypes. METHODS: Bi-allelic sequence-based typing and Luminex DNA PCR-SSOP assay were applied for the initial or repeat HLA typing, respectively. The rare HLA alleles were confirmed with mono-allelic sequence-based typing. Predicted haplotypes of the rare alleles were inferred based on the frequencies of HLA alleles...

Topics

Alleles
Asian People
Gene Frequency
HLA-A Antigens
HLA-B Antigens
HLA-DRB1 Chains
Haplotypes
Humans

Source

Open in PubMed

Identifiers

PMID: 25119926
DOI: 10.3760/cma.j.issn.1003-9406.2014.04.025

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