Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Silencing of <i>microRNA‐122</i> is an early event during hepatocarcinogenesis from non‐alcoholic steatohepatitis

13 Aug 2014

Abstract excerpt

Non-alcoholic steatohepatitis (NASH) has emerged as a common cause of chronic liver disease and virus-independent hepatocellular carcinoma (HCC) in patients with obesity, diabetes, and metabolic syndrome. To reveal the molecular mechanism underlying hepatocarcinogenesis from NASH, microRNA (miRNA) expression profiles were analyzed in STAM mice, a NASH-HCC animal model. MicroRNA expression was also examined in 42...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Liver Disease Diagnosis and Treatment
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25117675
DOI: 10.1111/cas.12498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Silencing of <i>microRNA‐122</i> is an early event during hepatocarcinogenesis from non‐alcoholic steatohepatitisPMID 25117675Read ↗

MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesisSemantic proximity Read ↗

Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expressionSemantic proximity Read ↗

MicroRNAs in liver disease.Semantic proximity Read ↗

Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis.Semantic proximity Read ↗

Circulating MicroRNA‐122 and Fibrosis Stage Predict Mortality of Japanese Patients With Histopathologically Confirmed NAFLDSemantic proximity Read ↗

A circulating microRNA signature as noninvasive diagnostic and prognostic biomarkers for nonalcoholic steatohepatitisSemantic proximity Read ↗

Hepatitis C virus' Achilles' heel--dependence on liver-specific microRNA miR-122.Semantic proximity Read ↗

microRNA-122 Abundance in Hepatocellular Carcinoma and Non-Tumor Liver Tissue from Japanese Patients with Persistent HCV versus HBV InfectionSemantic proximity Read ↗

Antiviral therapy reduces hepatocellular carcinoma through suppressing hepatitis B virus replication may improve ER stress, mitochondrial and metabolic dysfunctions and decrease p62 in hybridized mice with single HBV transgene and miR‐122Semantic proximity Read ↗

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus InfectionSemantic proximity Read ↗

Gene Expression and DNA Methylation Alterations During Non-alcoholic Steatohepatitis-Associated Liver CarcinogenesisSemantic proximity Read ↗

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.