Article
Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis.
Gut - 1 May 2015
Pirola Carlos J, Fernández Gianotti Tomas, Castaño Gustavo O, Mallardi Pablo, San Martino Julio, Mora Gonzalez Lopez Ledesma María, Flichman Diego, Mirshahi Faridodin, Sanyal Arun J, Sookoian Silvia
Abstract excerpt
OBJECTIVES: We used a screening strategy of global serum microRNA (miRNA) profiling, followed by a second stage of independent replication and exploration of liver expression of selected miRNAs to study: (1) the circulating miRNA signature associated with non-alcoholic fatty liver disease (NAFLD) progression and predictive power, (2) the role of miRNAs in disease biology and (3) the association between...
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