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Article

Association of common SNP rs1136410 in PARP1 gene with the susceptibility to male infertility with oligospermia.

Journal of assisted reproduction and genetics - 1 Oct 2014

Chen Hui, Pu Xiao-Ying, Zhang Ruo-Peng, A Zhou-Cun

Abstract excerpt

PURPOSE: This study aims to explore possible associations between polymorphisms of common SNP rs1136410 and rS1805405 in PARP1 gene and male infertility with spermatogenesis impairment. METHODS: The polymorphic distributions of SNP rs1136410 and rS1805405 were investigated by polymerase chain reaction and restriction fragment length polymorphism analysis in a Chinese cohort including 371 infertile patients with...

Topics

Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Asian People

Azoospermia

Gene Frequency

Genetic Predisposition to Disease

Genotype

Humans

Infertility, Male

Male

Oligospermia

Poly (ADP-Ribose) Polymerase-1

Poly(ADP-ribose) Polymerases

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 25106941
DOI: 10.1007/s10815-014-0311-3
PMCID: PMC4171409

Genes

PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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