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Article

Genetic polymorphisms and haplotypes of the DJ-1 gene promoter associated with the susceptibility to male infertility.

Journal of assisted reproduction and genetics - 1 Dec 2017

Jahantigh Danial, Hosseinzadeh Colagar Abasalt, Salimi Saeedeh

Abstract excerpt

PURPOSE: In this study, we evaluate the relationship between genetic polymorphisms of the DJ-1 gene, g.-6_+10del, and g.168_185del with male infertility susceptibility. METHODS: Four hundred and twenty-two male infertile patients and 285 fertile male controls were recruited. Genotyping was performed by polymerase chain reaction. In silico analysis was performed by EPD, ElemeNT, SNPnexus, and PROMO to predict the...

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Genetic Predisposition to Disease
Genotype
Haplotypes
Infertility, Male
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Protein Deglycase DJ-1

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Identifiers

PMID: 28932933
DOI: 10.1007/s10815-017-1033-0
PMCID: PMC5714825

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