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Article

A4383C and C76G SNP in Cathepsin B is respectively associated with the high risk and tumor size of hepatocarcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Nov 2014

Chen Tsung-Po, Yang Shun-Fa, Lin Chiao-Wen, Lee Hsiang-Lin, Tsai Chiung-Man, Weng Chia-Jui

Abstract excerpt

Single nucleotide polymorphism (SNP) in some genes is a candidate for having or developing a cancer. Cathepsin B (CTSB) is considered to be the biomarker of cancers. The study aimed to evaluate the impacts of three SNPs in CTSB gene on the risk and progress of hepatocellular carcinoma (HCC). The SNPs of CTSB C76G (rs12338), CTSB A4383C (rs13332), and CTSB A8422G (rs8898) from 135 patients with HCC and 520 control...

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Source

Identifiers

PMID: 25106406
DOI: 10.1007/s13277-014-2004-z

Genes

CTSB

Variants

rs12338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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