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Article

A phenome-guided drug repositioning through a latent variable model.

BMC bioinformatics - 8 Aug 2014

Bisgin Halil, Liu Zhichao, Fang Hong, Kelly Reagan, Xu Xiaowei, Tong Weida

Abstract excerpt

BACKGROUND: The phenome represents a distinct set of information in the human population. It has been explored particularly in its relationship with the genome to identify correlations for diseases. The phenome has been also explored for drug repositioning with efforts focusing on the search space for the most similar candidate drugs. For a comprehensive analysis of the phenome, we assumed that all phenotypes...

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Identifiers

PMID: 25103881
DOI: 10.1186/1471-2105-15-267
PMCID: PMC4137076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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