Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influenza A virus acquires enhanced pathogenicity and transmissibility after serial passages in swine.

Journal of virology - 1 Oct 2014

Wei Kai, Sun Honglei, Sun Zhenhong, Sun Yipeng, Kong Weili, Pu Juan, Ma Guangpeng, Yin Yanbo, Yang Hanchun, Guo Xin, Chang Kin-Chow, Liu Jinhua

Abstract excerpt

Genetic and phylogenetic analyses suggest that the pandemic H1N1/2009 virus was derived from well-established swine influenza lineages; however, there is no convincing evidence that the pandemic virus was generated from a direct precursor in pigs. Furthermore, the evolutionary dynamics of influenza virus in pigs have not been well documented. Here, we subjected a recombinant virus (rH1N1) with the same...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bronchoalveolar Lavage Fluid
Share to Dogs

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Guinea Pigs

Share to Influenza A virus

Share to Orthomyxoviridae Infections

Share to Serial Passage

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 25100840
DOI: 10.1128/JVI.01679-14
PMCID: PMC4178715

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influenza A virus acquires enhanced pathogenicity and transmissibility after serial passages in swine.PMID 25100840Read ↗

Pathogenicity and Transmissibility of Novel Reassortant H3N2 Influenza Viruses with 2009 Pandemic H1N1 Genes in PigsSemantic proximity Read ↗

Transmission and pathogenicity of novel reassortants derived from Eurasian avian-like and 2009 pandemic H1N1 influenza viruses in mice and guinea pigs.Semantic proximity Read ↗

Reassortment between Swine H3N2 and 2009 Pandemic H1N1 in the United States Resulted in Influenza A Viruses with Diverse Genetic Constellations with Variable Virulence in Pigs.Semantic proximity Read ↗

Transmission and pathologic findings of divergent human seasonal H1N1pdm09 influenza A viruses following spillover into pigs in the United StatesSemantic proximity Read ↗

A Eurasian avian-like H1N1 swine influenza reassortant virus became pathogenic and highly transmissible due to mutations in its PA gene.Semantic proximity Read ↗

Analysis of Recombinant H7N9 Wild-Type and Mutant Viruses in Pigs Shows that the Q226L Mutation in HA Is Important for TransmissionSemantic proximity Read ↗

Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection.Semantic proximity Read ↗

Multiple reassortment between pandemic (H1N1) 2009 and endemic influenza viruses in pigs, United States.Semantic proximity Read ↗

Naturally occurring influenza reassortment in pigs facilitates the emergence of intrahost virus subpopulations with distinct genotypes and replicative fitness.Semantic proximity Read ↗

Effect of serial pig passages on the adaptation of an avian H9N2 influenza virus to swine.Semantic proximity Read ↗

H5N1 hybrid viruses bearing 2009/H1N1 virus genes transmit in guinea pigs by respiratory droplet.Semantic proximity Read ↗

Tissue tropisms of avian influenza A viruses affect their spillovers from wild birds to pigsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.