Article
Advanced onset of puberty after metformin therapy in swine with thrifty genotype.
Experimental physiology - 1 Sept 2014
Astiz S, Gonzalez-Bulnes A, Astiz I, Barbero A, Perez-Solana M L, Garcia-Real I
Abstract excerpt
The prevention and treatment of obesity in children is based on adequate nutrition and exercise plus antihyperglycaemic drugs. Currently, the incidence of childhood obesity is aggravated in ethnicities with thrifty genotype, but there is no available information on the effects of metformin therapy. The relative effects of lifestyle and metformin on patterns of growth, fattening, metabolic status and attainment of...
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