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Article

Basal cell carcinomas: attack of the hedgehog.

Nature reviews. Cancer - 1 Oct 2008

Epstein Ervin H

Abstract excerpt

Basal cell carcinomas (BCCs) were essentially a molecular 'black box' until some 12 years ago, when identification of a genetic flaw in a rare subset of patients who have a great propensity to develop BCCs pointed to aberrant Hedgehog signalling as the pivotal defect leading to formation of these tumours. This discovery has facilitated a remarkable increase in our understanding of BCC carcinogenesis and has...

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Identifiers

PMID: 18813320
DOI: 10.1038/nrc2503
PMCID: PMC4457317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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