Article
Mammalian cellular culture models of Trypanosoma cruzi infection: a review of the published literature.
Parasite (Paris, France) - 1 Jan 2014
Duran-Rehbein Gabriel Alberto, Vargas-Zambrano Juan Camilo, Cuéllar Adriana, Puerta Concepción Judith, Gonzalez John Mario
Abstract excerpt
Cellular culture infection with Trypanosoma cruzi is a tool used to dissect the biological mechanisms behind Chagas disease as well as to screen potential trypanocidal compounds. Data on these models are highly heterogeneous, which represents a challenge when attempting to compare different studies. The purpose of this review is to provide an overview of the cell culture infectivity assays performed to date....
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