Article
Dietary supplementation of omega-3 fatty acids rescues fragile X phenotypes in Fmr1-Ko mice.
Psychoneuroendocrinology - 1 Nov 2014
Pietropaolo Susanna, Goubran Mina G, Joffre Corinne, Aubert Agnes, Lemaire-Mayo Valerie, Crusio Wim E, Layé Sophie
Abstract excerpt
Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are known to critically influence brain development and functions. Dietary supplementation with n-3 PUFAs has been suggested as a non-pharmacological therapy for a number of developmental disorders, e.g., autistic spectrum disorders (ASD), but human studies so far have led to conflicting results. Furthermore, it has been hypothesized that the therapeutic impact of...
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