Article
Tissue triage and freezing for models of skeletal muscle disease.
Journal of visualized experiments : JoVE - 15 Jul 2014
Meng Hui, Janssen Paul M L, Grange Robert W, Yang Lin, Beggs Alan H, Swanson Lindsay C, Cossette Stacy A, Frase Alison, Childers Martin K, Granzier Henk, Gussoni Emanuela, Lawlor Michael W
Abstract excerpt
Skeletal muscle is a unique tissue because of its structure and function, which requires specific protocols for tissue collection to obtain optimal results from functional, cellular, molecular, and pathological evaluations. Due to the subtlety of some pathological abnormalities seen in congenital muscle disorders and the potential for fixation to interfere with the recognition of these features, pathological...
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