Article
SlmA antagonism of FtsZ assembly employs a two-pronged mechanism like MinCD.
PLoS genetics - 1 Jul 2014
Du Shishen, Lutkenhaus Joe
Abstract excerpt
Assembly of the Z-ring over unsegregated nucleoids is prevented by a process called nucleoid occlusion (NO), which in Escherichia coli is partially mediated by SlmA. SlmA is a Z ring antagonist that is spatially regulated and activated by binding to specific DNA sequences (SlmA binding sites, SBSs) more abundant in the origin proximal region of the chromosome. However, the mechanism by which SBS bound SlmA...
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