Article
Metabolic complete tumor response in a patient with epidermal growth factor receptor mutant non-small cell lung cancer treated with a reduced dose of afatinib.
The Journal of international medical research - 1 Mar 2022
Puliafito Ivana, Esposito Francesca, Raciti Gabriele, Giuffrida Paolo, Caltavuturo Claudia, Colarossi Cristina, Munao Stefania, Sciacca Dorotea, Giuffrida Dario
Abstract excerpt
Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) are the first-line treatment for EGFR-mutant non-small cell lung cancer. Toxicities related to EGFR-TKIs include skin rash, paronychia, and diarrhea, which in some cases can lead to dose reductions or treatment interruptions. Herein, we report the case of a 51-year-old woman affected by advanced adenocarcinoma harboring an exon 19...
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