Article
Unique volatolomic signatures of TP53 and KRAS in lung cells.
British journal of cancer - 9 Sept 2014
Davies M P A, Barash O, Jeries R, Peled N, Ilouze M, Hyde R, Marcus M W, Field J K, Haick H
Abstract excerpt
BACKGROUND: Volatile organic compounds (VOCs) are potential biomarkers for cancer detection in breath, but it is unclear if they reflect specific mutations. To test this, we have compared human bronchial epithelial cell (HBEC) cell lines carrying the KRAS(V12) mutation, knockdown of TP53 or both with parental HBEC cells. METHODS: VOC from headspace above cultured cells were collected by passive sampling and...
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