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Article

Ruling in or ruling out thyroid malignancy by molecular diagnostics of thyroid nodules.

Best practice & research. Clinical endocrinology & metabolism - 1 Aug 2014

Eszlinger Markus, Hegedüs László, Paschke Ralf

Abstract excerpt

Routine morphologic cytology is the basis for any kind of (integrated) molecular FNA diagnostics. The rule out (gene expression classifier) approach requires confirmation by independent studies, whereas the rule in approach (detection of BRAF, NRAS, HRAS, and KRAS and PAX8/PPARG- and RET/PTC rearrangements) has been investigated by several groups with overall reproducible results. Moreover, molecular screening...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25047205
DOI: 10.1016/j.beem.2014.01.011

Genes

BRAF
HRAS
KRAS
NRAS
PAX8
PPARG
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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