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Article

Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling.

Journal of neurochemistry - 1 Nov 2014

Santhanam Anantha Vijay R, d'Uscio Livius V, Katusic Zvonimir S

Abstract excerpt

This study was designed to determine whether treatment with erythropoietin (EPO) could protect cerebral microvasculature against the pathological consequences of endothelial nitric oxide (NO) synthase uncoupling. Wild-type and GTP cyclohydrolase I (GTPCH-I)-deficient hph1 mice were administered E...

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Source

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Identifiers

PMID: 25041251
DOI: 10.1111/jnc.12824
PMCID: PMC4222993

Genes

EPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25041251-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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