Article
Maturity onset diabetes of the young in India - a distinctive mutation pattern identified through targeted next-generation sequencing.
Clinical endocrinology - 1 Apr 2015
Chapla Aaron, Mruthyunjaya Mahesh Doddabelavangala, Asha Hesarghatta Shyamasunder, Varghese Denny, Varshney Manika, Vasan Senthil K, Venkatesan Padmanaban, Nair Veena, Mathai Sarah, Paul Thomas Vizhalil, Thomas Nihal
Abstract excerpt
OBJECTIVE: To establish and utilize a Next-Generation Sequencing (NGS)-based strategy to screen for maturity onset diabetes of the young (MODY) gene mutations in subjects with early-onset diabetes. PATIENTS AND METHODS: Maturity onset diabetes of the young (MODY) genetic testing was carried out in 80 subjects of Asian Indian origin with young onset diabetes to identify mutations in a comprehensive panel of ten...
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