Article
RTN4 3'-UTR insertion/deletion polymorphism and susceptibility to non-small cell lung cancer in Chinese Han population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Lu De-Yi, Mao Xu-Hua, Zhou Ying-Hui, Yan Xiao-Long, Wang Wei-Ping, Zheng Ya-Biao, Xiao Juan-Juan, Zhang Ping, Wang Jian-Guo, Ashwani Neetika, Ding Wei-Liang, Jiang Hua, Shang Yan, Wang Ming-Hua
Abstract excerpt
Nogo protein, encoded by gene reticulon-4 (RTN4), includes three major isoforms by different splicing, named Nogo-A Nogo-B and Nogo-C. Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. RTN4 single nucleotide polymorphisms (SNPs) can influence the efficiency of transcription and translation thus being related with an individual's predisposition to cancer. The CAA...
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