Article
Linkage disequilibrium over short physical distances measured in sheep using a high-density SNP chip.
Animal genetics - 1 Oct 2014
Kijas James W, Porto-Neto Laercio, Dominik Sonja, Reverter Antonio, Bunch Rowan, McCulloch Russell, Hayes Ben J, Brauning Rudiger, McEwan John
Abstract excerpt
The extent of linkage disequilibrium (LD) between genetic loci has implications for both association studies and the accuracy of genomic prediction. To characterise the persistence of LD in diverse sheep breeds, two SNP genotyping platforms were used. First, existing SNP genotypes from 63 breeds obtained using the ovine SNP50 BeadChip (49,034 loci) were used to estimate LD decay in populations with contrasting...
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