Article
Regulatory T cell microRNA expression changes in children with acute Kawasaki disease.
Clinical and experimental immunology - 1 Nov 2014
Ni F-F, Li C-R, Li Q, Xia Y, Wang G-B, Yang J
Abstract excerpt
Kawasaki disease (KD) is a type of systemic vasculitis syndrome related to immune dysfunction. Previous studies have implicated that dysfunctional regulatory T cells (Treg ) may be associated with the immune dysfunction in KD. In the absence of microRNAs (miRNAs), forkhead box protein 3 (FoxP3)(+) Treg develop but fail to maintain immune homeostasis. This study was designed to investigate the effects of miR-155,...
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