Article
Multiple FLC haplotypes defined by independent cis-regulatory variation underpin life history diversity in Arabidopsis thaliana.
Genes & development - 1 Aug 2014
Li Peijin, Filiault Daniele, Box Mathew S, Kerdaffrec Envel, van Oosterhout Cock, Wilczek Amity M, Schmitt Johanna, McMullan Mark, Bergelson Joy, Nordborg Magnus, Dean Caroline
Abstract excerpt
Relating molecular variation to phenotypic diversity is a central goal in evolutionary biology. In Arabidopsis thaliana, FLOWERING LOCUS C (FLC) is a major determinant of variation in vernalization--the acceleration of flowering by prolonged cold. Here, through analysis of 1307 A. thaliana accessions, we identify five predominant FLC haplotypes defined by noncoding sequence variation. Genetic and transgenic...
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