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Article

Epistatic interaction between Arabidopsis FRI and FLC flowering time genes generates a latitudinal cline in a life history trait.

Proceedings of the National Academy of Sciences of the United States of America - 2 Nov 2004

Caicedo Ana L, Stinchcombe John R, Olsen Kenneth M, Schmitt Johanna, Purugganan Michael D

Abstract excerpt

Epistatic gene interactions are believed to be a major factor in the genetic architecture of evolutionary diversification. In Arabidopsis thaliana, the FRI and FLC genes mechanistically interact to control flowering time, and here we show that this epistatic interaction also contributes to a latitudinal cline in this life history trait within the species. Two major FLC haplogroups (FLC(A) and FLC(B)) are...

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Identifiers

PMID: 15505218
DOI: 10.1073/pnas.0406232101
PMCID: PMC524852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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