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Article

Co-mutated pathways analysis highlights the coordination mechanism in glioblastoma multiforme.

Neoplasma - 1 Jan 2014

Wei B, Wang L, Zhao X, Jin Y, Kong D, Hu G, Sun Z

Abstract excerpt

The mutation of cancer represents a high heterogeneity characteristic, setting a big obstacle in the mechanism study of it. In this study, we explored the distributions of mutated genes in pathways in glioblastoma multiforme (GBM), and constructed networks of co-mutated pathway pairs under the false discovery rate (FDR) control. By comparing the mutation frequencies, a total of 50 mutated genes were screened with...

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Source

Identifiers

PMID: 25027741
DOI: 10.4149/neo_2014_052

Genes

EGFR
PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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