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Article

Selection variability for Arg48His in alcohol dehydrogenase ADH1B among Asian populations.

Human biology - 1 Aug 2013

Evsyukov Alexey, Ivanov Denis

Abstract excerpt

The variant His at codon 48 of the alcohol dehydrogenase gene (ADH1B) results in more efficient ethanol metabolism than with the "typical" codon 48Arg. In this study we introduced selection properties of Arg48His genotypes of ADH1B and estimated fitness in four ethnic-geographical clusters in Asia. Population genetics models were employed that derive observed gene frequencies from fitness relationships among...

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Identifiers

PMID: 25019189
DOI: 10.3378/027.085.0404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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