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Article

Utilizing FMR1 gene mutations as predictors of treatment success in human in vitro fertilization.

PloS one - 1 Jan 2014

Kushnir Vitaly A, Yu Yao, Barad David H, Weghofer Andrea, Himaya Eric, Lee Ho-Joon, Wu Yan-Guang, Shohat-Tal Aya, Lazzaroni-Tealdi Emanuela, Gleicher Norbert

Abstract excerpt

CONTEXT: Mutations of the fragile X mental retardation 1 (FMR1) gene are associated with distinct ovarian aging patterns. OBJECTIVE: To confirm in human in vitro fertilization (IVF) that FMR1 affects outcomes, and to determine whether this reflects differences in ovarian aging between FMR1 mutations, egg/embryo quality or an effect on implantation. DESIGN, SETTING, PATIENTS: IVF outcomes were investigated in a...

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Share to Fragile X Mental Retardation Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25019151
DOI: 10.1371/journal.pone.0102274
PMCID: PMC4096763

Genes

FMR1

Provenance

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