Article
Mutant phenotype analysis suggests potential roles for C-type natriuretic peptide receptor (NPR-B) in male mouse fertility.
Reproductive biology and endocrinology : RB&E - 10 Jul 2014
Sogawa Chizuru, Fujiwara Yasuhiro, Tsukamoto Satoshi, Ishida Yuka, Yoshii Yukie, Furukawa Takako, Kunieda Tetsuo, Saga Tsuneo
Abstract excerpt
BACKGROUND: C-type natriuretic peptide (CNP) signaling through its receptor natriuretic peptide receptor B (NPR-B) is a key molecule for mammalian reproduction, and known to play important roles in female fertility. However, the function of these peptides in mouse male reproduction remains largely unknown. To determine the role of CNP/NPR-B signaling in male reproduction we investigated phenotype of...
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